Breaking the Therapeutic Ceiling in Autoimmunity

We are building the world’s deepest Autoimmune Foundation Model, anchored by single-cell & spatial data matched with longitudinal clinical outcomes.

Supervised Representation Learning & Generative AI

At the core of ScaiVision™ is our proprietary Supervised Representation Learning method. This unbiased, cluster-free approach identifies complex molecular patterns associated with clinical outcomes without needing pre-defined cell types. This allows us to discover novel biological signals at unprecedented resolution and sensitivity, and subsequently to translate these discoveries into clinical assets.

With our new focus on autoimmune diseases, we have expanded our AI platform by training and refining Deep Generative and Single-Cell Foundation Models on vast amounts of patient-derived single-cell and spatial omics data. These powerful data models enable predictive disease modeling and patient endotyping at scale.

Our IBD Flagship Program

3.6mln

Single-cell profiles

500+

patients

1000+

samples

Breaking the Therapeutic Ceiling

Despite the rise of biologic disease-modifying drugs, a profound therapeutic ceiling persists in Inflammatory Bowel Disease (IBD). Primary non-response rates reach as high as 41% in Ulcerative Colitis (UC) and Crohn's Disease (CD), and nearly 70% of all IBD patients fail to achieve durable remission with first-line biologics.

Traditional R&D has hit a wall because it relies on bulk data that obscures the cellular heterogeneity driving treatment resistance. Scailyte’s IBD Flagship Program decodes this complexity through advanced patient endotyping, providing pharma partners with the high-resolution map needed to navigate the immunology market which is evolving towards high-efficacy precision treatments.

The World’s Deepest IBD Data Asset

We have established an industry-leading discovery platform focused on IBD and immunotherapies. The platform is fueled by the largest (and growing) tissue single-cell omics IBD Atlas, complemented with multiple other data modalities and longitudinal clinical data. In order to gain the best insights from this rich data, we have deployed a Family of AI Models tailored for high-dimensional, single-cell biology.

Unmatched Scale: We are continuously expanding our single-cell and spatial omics data lake and turning it into a harmonized and insights-ready disease model.

Exclusive Clinical Access: Our IBD Program is anchored by the Swiss IBD Cohort (4,000+ patients, 15+ years of longitudinal data, 40,000+ samples) and a network of leading KOLs providing clinical samples and data from longitudinal national cohorts in IBD and other autoimmune diseases.

Unmatched Scale: We are continuously expanding our single-cell and spatial omics data lake and turning it into a harmonized and insights-ready disease model.


Exclusive Clinical Access: Our IBD Program is anchored by the Swiss IBD Cohort (4,000+ patients, 15+ years of longitudinal data, 40,000+ samples) and a network of leading KOLs providing clinical samples and data from longitudinal national cohorts in IBD and other autoimmune diseases.

SWISSIBDcohort

Strategic Avenues for Pharma Partnerships

1. Asset De-Risking & Trial Stratification

Rescue stalled programs or optimize Phase 2/3 designs. By performing in silico validation using our IBD Foundation Model, we achieve high-resolution patient endotyping, identifying precise responder signatures to ensure your asset reaches the right population.

1. Asset De-Risking & Trial Stratification

2. Target Discovery & Combo Positioning

Fill your pipeline with first-in-class assets designed for refractory populations. We leverage deep spatial-omics to map the biological mechanistic escape routes that lead to Anti-TNF and JAKi failure in CD and UC, uncovering novel targets and rational combination therapies.

2. Target Discovery & Combo Positioning

3. Precision Diagnostics

Strengthen your market position by co-developing predictive biomarkers. We transform discovery-stage insights into robust biomarker assays that serve as Companion Diagnostics (CDx), ensuring high response rates and clear clinical differentiation through molecular-level patient endotyping.

3. Precision Diagnostics

Interested in partnership opportunities?

Scailyte AG 𑇐 Lichtstrasse 35 𑇐 4056 Basel 𑇐 Switzerland

Scailyte 2026 © All rights reserved. Scailyte, ScaiVision and the Scailyte logo are registered trademarks.

Scailyte 2026 © All rights reserved. Scailyte, ScaiVision and the Scailyte logo are registered trademarks.

Interested in partnership opportunities?