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Enabling precision medicine with explainable AI and multi-omics data

We are a precision medicine company committed to solving healthcare's toughest challenges. Scailyte develops a pipeline of breakthrough diagnostic and companion diagnostic (CDx) solutions, powered by our unique ScaiVision AI platform and deep multimodal data insights, to ensure every patient receives the most effective treatment.

USZ Zurich
Inselspital
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The healthcare problem we solve

The promise of modern medicine is immense, yet critical challenges persist in delivering truly personalized care:

The Efficacy Gap: Matching Patients to Effective Therapies

A critical challenge in modern medicine is the ‘efficacy gap.’ Even for advanced treatments in complex areas like immune-mediated diseases and oncology, response rates often hit a therapeutic ceiling, with maximum 30-40% of patients experiencing therapeutic response. This means many individuals may not receive the life-changing impact a therapy can offer, underscoring the urgent, unmet need to accurately identify the right therapy for the right patient.

Deep Biological Complexity

Deep Biological Complexity

The efficacy gap directly stems from vast biological complexity. Hundreds of interacting cell types across diverse tissues drive individual disease courses and treatment responses, particularly in immune-related conditions and cancer. Truly understanding these intricate mechanisms to develop accurate diagnostic or predictive assays requires high-resolution measurements at the cellular and molecular level. 

The Untapped Potential of Big Data

The Untapped Potential of Big Data

While cutting-edge technologies now generate a ‘tsunami’ of the necessary high-resolution biological data, this presents its own significant hurdle. The sheer volume, dimensionality, and complexity of this ‘big data’ can overwhelm conventional analytical tools, often failing to extract clear, actionable intelligence. There is a profound need for advanced analytical capabilities and tailored AI-driven approaches to navigate this data deluge and provide the precise answers required to guide truly personalized treatment decisions.

12 successful discovery projects

1000+ single cell samples analyzed

50 Billion data points

The Scailyte Solution: Deep Insights turned into Clinical Breakthroughs

The full promise of powerful medicines, such as immuno-therapies, is often unrealized due to highly variable patient responses and an incomplete understanding of the factors defining these responses. This results in a trial-and-error approach to treatment selection, often causing unnecessary patient suffering, poor outcomes, and massive healthcare costs. Scailyte directly confronts this critical healthcare and societal challenge, guided by two key principles: deep biological understanding and patient impact. Our integrated approach combines multiple data modalities and our cutting-edge AI into a translational research platform that yields impactful precision medicine products. As pioneers in single-cell data discovery since 2017, we have developed a pipeline of diagnostic and predictive biomarkers tackling some of the most pressing clinical and therapeutic hurdles, often in novel ways.

Foundation: Unparalleled Data

Foundation: Unparalleled Data

We harness the power of high-resolution, multimodal omics data. Our expertise lies in generating and integrating these rich datasets, often leveraging our unique clinical network access or working with partner-provided data, to create an unparalleled foundation for discovering the subtle signals that fuel our diagnostic and CDx pipeline.

ScaiVision: Our Proprietary Explainable AI Engine

ScaiVision: Our Proprietary Explainable AI Engine

At the heart of our capability is ScaiVision, our proprietary and best-in-class explainable AI platform. It expertly navigates the ‘noise’ within these massive datasets, pinpointing critical signals and biological drivers that conventional methods often miss, providing the engine for our innovative product development.

Translating Discovery into Our Clinical Solutions

Translating Discovery into Our Clinical Solutions

We decipher intricate disease biology, understand drug mechanisms of action (MoA) and resistance, and develop precise predictive biomarkers for patient sub-population identification and treatment response. These discoveries are then rigorously translated by our team into robust, clinically validated assays and decision support tools designed to empower clinicians and transform patient outcomes.

Why Scailyte? Beyond Conventional AI: Our Definitive Advantage in Precision Medicine.

Gain superior speed, robustness, translatability and unmatched discovery potential
Accelerated Path to Our Clinical Solutions:

Accelerated Path to Our Clinical Solutions:

Our advanced AI and streamlined processes dramatically reduce timelines from complex multimodal data to validated biological insights. This speed enables Scailyte to rapidly advance our pipeline of innovative diagnostic and CDx solutions from concept to clinical readiness. With continuous automation and technological evolution, our R&D timelines are getting shorter and shorter, while our capacity to run multiple clinical programs in parallel is scaling up.

Superior Discovery Power for Our Pipeline:

Superior Discovery Power for Our Pipeline:

ScaiVision identifies elusive disease drivers and highly predictive signatures with unparalleled sensitivity and specificity. This exceptional discovery power allows Scailyte to pioneer novel diagnostic approaches and identify unique therapeutic opportunities that fuel our pipeline of precision medicine products.

From a Black Box to Biological Truth: ​

From a Black Box to Biological Truth:

Our Explainable AI delivers fully transparent and interpretable results. This provides deep biological understanding that empowers Scailyte's confident, data-driven decisions and defines clear pathways for translating our internal discoveries into simplified clinical assays for diagnostics and CDx solutions.

Proven Performance, Unwavering Reliability:

Proven Performance, Unwavering Reliability:

Leveraging our pioneering expertise in AI-driven single-cell discovery, Scailyte's platform delivers highly robust and reproducible findings. This proven performance and unwavering reliability are foundational to developing our pipeline of trusted, high-impact clinical solutions.

clinical trials

Exclusive Data Access: Fueling Our Next-Generation Diagnostics & CDx

Through our established clinical network, Scailyte gains privileged access to unique patient cohorts and deep multimodal real-world data, especially in oncology and immunology. This direct line to clinical reality fuels the discovery and validation of highly relevant and impactful signatures that form the core of our diagnostic and CDx pipeline.

Scailyte is committed to developing next-generation precision medicine products that break the therapeutic ceiling and enable high efficacy treatments for all patients. Our discovery pipeline features promising diagnostic and CDx candidates, each born from deep biological understanding derived from our unique data access and the analytical power of ScaiVision AI. These solutions aim to transform patient outcomes in challenging therapeutic areas by paving the way for more personalized and effective healthcare.

Learn about our solutions for drug developers
Hemex

Partner Testimonials

Meghan Verschoor

Meghan Verschoor

Associate Director, Data Science in Clinical and Translational Medicine at Turnstone Biologics

“Our team is very impressed with the level of attention to detail and domain knowledge that the Scailyte team brings to our project. We’re excited to continue working with your team!”
Thomas Mehrling

Thomas Mehrling

MD PhD, CEO of MaxiVAX

“Scailyte has been instrumental in analyzing phase IIa clinical single-arm trial data of our most advanced development program. Scailyte’s scientific expertise, communication style and agility are commendable”
Prof. Dr Michael Mueller

Prof. Dr Michael Mueller

Leading Clinician in Women’s Health & Scientific Advisor

“Our current collaboration with Scailyte in the field of women’s health is a truly innovative approach. We are integrating cutting edge technologies to develop biomarkers that will be the basis for impactful diagnostic solutions.”
Pascal Koenig

Pascal Koenig

Entrepreneur & Chairman of the Board of Directors

“As the co-founder and former CEO of Ava Women, I have experienced the power that big datasets have on the healthcare industry. Scailyte’s mission, proven technology and strong expertise have convinced me to join the team. I am delighted to contribute and assist in bringing Scailyte’s solution to patients around the world.”

Recent News

Scailyte and Sanofi Collaboration Solves Critical Manufacturing Challenge for NK Cell Therapy, New Paper Reveals

Scailyte's AI-driven ScaiVision™ platform successfully identified a predictive biomarker for manuf...

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Recent News

Scailyte Awarded CHF 800K Innosuisse Grant to Drive Precision Medicine in Inflammatory Bowel Disease (IBD)

Project AIomics will unite Scailyte's AI discovery platform with the Swiss IBD Cohort and Universit...

Read more

Recent News

Scailyte and Visterra Partner to Advance Autoimmune Disease Research

Scailyte AG, an AI-driven biomarker discovery company, and Visterra, Inc., a clinical-stage biopharm...

Read more

Recent News

Scailyte Strengthens Its Leadership

Scailyte appoints Tim Foley as Chief Business Officer, Jean-Pierre Rosat as Executive Chair, and Dar...

Read more

Recent News

Scailyte Announces Virginia Savova, PhD as a Strategic and Scientific Advisor

Scailyte Announces Virginia Savova, PhD as a Strategic and Scientific Advisor. Dr. Savova brings str...

Read more

Recent News

Scailyte Extends Series A to USD 8 Million

We are thrilled to announce the extension of our Series A funding, bringing the total raised amount ...

Read more

Recent News

Unravelling the AI Executive Order: A Discussion with Our CEO and Head of Regulatory Affairs

We invite you to watch this enlightening discussion to gain valuable insights into the evolving AI l...

Read more

Recent News

Scailyte and MaxiVAX Solve Clinical Challenges with Data-Driven Collaboration

Scailyte and MaxiVAX, two cutting-edge precision medicine organizations, proudly announce their coll...

Read more

Recent News

01 /04

Scailyte and Sanofi Collaboration Solves Critical Manufacturing Challenge for NK Cell Therapy, New Paper Reveals

Scailyte's AI-driven ScaiVision™ platform successfully identified a predictive biomarker for manuf...

Read more

Scailyte Awarded CHF 800K Innosuisse Grant to Drive Precision Medicine in Inflammatory Bowel Disease (IBD)

Project AIomics will unite Scailyte's AI discovery platform with the Swiss IBD Cohort and Universit...

Read more

Recent News

02 /04

Scailyte and Visterra Partner to Advance Autoimmune Disease Research

Scailyte AG, an AI-driven biomarker discovery company, and Visterra, Inc., a clinical-stage biopharm...

Read more

Scailyte Strengthens Its Leadership

Scailyte appoints Tim Foley as Chief Business Officer, Jean-Pierre Rosat as Executive Chair, and Dar...

Read more

Recent News

03 /04

Scailyte Announces Virginia Savova, PhD as a Strategic and Scientific Advisor

Scailyte Announces Virginia Savova, PhD as a Strategic and Scientific Advisor. Dr. Savova brings str...

Read more

Scailyte Extends Series A to USD 8 Million

We are thrilled to announce the extension of our Series A funding, bringing the total raised amount ...

Read more

Recent News

04 /04

Unravelling the AI Executive Order: A Discussion with Our CEO and Head of Regulatory Affairs

We invite you to watch this enlightening discussion to gain valuable insights into the evolving AI l...

Read more

Scailyte and MaxiVAX Solve Clinical Challenges with Data-Driven Collaboration

Scailyte and MaxiVAX, two cutting-edge precision medicine organizations, proudly announce their coll...

Read more

Recent News

Dr. Peter Nestorov

Founder & Chief Executive Officer

Co-founder and Chief Executive Officer of Scailyte. He holds a PhD in genetics from the University of Basel and a degree in Biochemistry from the University of Tübingen.

During his PhD work, Dr. Nestorov pioneered the development and application of methods for single-cell analysis, which sparked his passion for this technology. In 2015, Dr. Nestorov joined Witec AG as Sales Specialist for single-cell and genomics technologies and successfully introduced the first commercial devices for single-cell analysis on the Swiss Life Science market. The interaction with biomedical researchers and the technological insight inspired Dr. Nestorov to start Scailyte and unlock the full clinical potential of single-cell data.

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Dr. Sarah Carl

Lead Data Scientist
is managing the Data Science division of Scailyte. She holds a PhD in Genetics and a Master’s degree in Developmental Biology from the University of Cambridge. Before joining Scailyte she was a post-doc and bioinformatician at the Friedrich Miescher Institute for Biomedical Research in Basel. At Scailyte she is leading the development of new applications and features of the internal data analysis platform, ScaiVision, and the data analysis of the clinical programmes.
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Anna Dimitrova, ACCA

Director Finance & Ops
Is the Director of Finance and Operations at Scailyte. She is an ACCA graduate with a Master’s degree in Finance and Banking from Sofia University. Before joining Scailyte she worked as Senior Audit Assistant at KPMG, Senior Business Consultant at PwC and as Finance Manager in a fast growing company in Bulgaria. At Scailyte she leads the finance, administration and internal operations of the company.

Pascal Winnen

CEO Hemex AG & Scailyte Board of Directors

Pascal is a co-founder and the CEO of HEMEX, a pharmaceutical, biotech and medical device consulting firm with offices in Switzerland, Germany and the USA. He holds a bachelor’s degree in Telecommunication Technologies from the University of Leuven (Belgium) and a master’s degree in Clinical Research from the Donau University in Krems (Austria). Pascal worked in various positions in the pharmaceutical and medtech industry.

From 2011 to 2015, Pascal worked for Finox Biotech, bringing one of the first biosimilar fertility treatments to the market in the EU and leading to the successful acquisition by Gedeon Richter for CHF 190 million. With his consulting firm HEMEX, Pascal has invested in multiple innovative life science startups, where he also advises on regulatory, clinical and marketing strategies, either as a senior consultant or as a board member.

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Dominique Mégret

Head of Swisscom Ventures & Scailyte Board of Directors
Dominique Mégret is head of Swisscom Ventures, which he started in 2007. He joined Swisscom in 2002 as head of the Group Strategy unit. Previously, Dominique Mégret was an entrepreneur in the United Kingdom, a strategy consultant in the European telecom industry and country manager for an IT company in Germany. He currently serves on the boards of Scailyte AG and Bloom SA. He is also an observer on the boards of Sophia Genetics and AVA Women.
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Prof. Dr. Manfred Claassen

Founder & Chief Scientific Advisor AI & Single-Cell Analysis
Co-founder and Chief Scientific Advisor at Scailyte. He holds degrees in both Biochemistry and Computer Science from the University of Tübingen and a PhD in the design and validation of proteome measurements from the ETH Zurich. He continued his academic path as a postdoctoral researcher at Stanford University’s Artificial Intelligence Lab focusing on research in machine learning for high dimensional single-cell biology, he moved back to Switzerland as an Assistant Professor at the ETH. During this time, the idea of establishing a company specialising in digital healthcare was conceived. Dr. Claassen was instrumental in conceptualizing the new company. He is now professor for clinical bioinformatics at the University of Tübingen, Germany in parallel with his role as scientific consultant for Scailyte.
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