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AI-driven single-cell data analysis identifies a cell signature predictive of neurotoxicity and clinical response in CAR-T cell therapy of DLBCL

AI-driven single-cell data analysis identifies a cell signature predictive of neurotoxicity and clinical response in CAR-T cell therapy of DLBCL

In our latest white paper, “AI-driven single-cell data analysis identifies a cell signature predictive of neurotoxicity and clinical response in CAR-T cell therapy of DLBCL”, we delve deep into the transformative impact of ScaiVision, Scailyte’s pioneering platform, on the realm of CAR-T cell therapy for Diffuse Large B-Cell Lymphoma (DLBCL).

Leveraging the power of single-cell omics alongside advanced AI, we’ve uncovered pivotal cellular signatures predictive of severe neurotoxicity and therapy response from a small dataset of 24 patient samples. Predicting treatment outcomes and identifying potential neurotoxicity risks has tremendous potential to ensure a safer, more tailored therapeutic journey for each patient treated by CAR-T therapies.

We invite you to explore the contribution of single-cell technologies and our AI-driven data analysis approach to advance CAR-T therapy.

Join us in this exciting journey towards a future where cancer treatment is not only effective but also uniquely personalized.

 

About Scailyte

Scailyte is an ETH Zürich spin-off with a best-in-class artificial intelligence platform for the discovery of complex disease patterns from single-cell data. Our solution provides unprecedented insight into the disease and patients’ biology and enables the discovery of new clinically-relevant biomarker signatures by uncovering human’s hidden “single-cell” secrets. 

Scailyte’s proprietary best-in-class data analysis platform ScaiVision™ associates multimodal single-cell datasets (RNA-/TCR-/BCR-seq, proteomics, etc.) with clinical endpoints, such as disease diagnosis, progression, severity, treatment response, and toxicity response to identify ultra-sensitive biomarker signatures and cell functionality states. The performance and clinically-relevant applications of Scailyte’s platform ScaiVision have been demonstrated in well established CAR-T cell therapies and various clinical projects in Oncology and Immunology.

For more information, visit www.scailyte.com and connect on social media @LinkedIn and @Twitter.

ScailyteTM and ScaiVisionTM are registered trademarks proprietary to Scailyte AG.

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