Skip to content

Machine learning meets multi-omics for precision medicine

Scailyte's 5th anniversary Mini-symposium - Machine learning meets multi-omics for precision medicine

Simultaneous analysis of millions of individual cells empowered with machine learning has potential to revolutionize treatments of many challenging human diseases including cancer, inflammatory and neurological disorders.

Biology has become a data science. For instance, recent single-cell profiling technologies are capable of measuring thousands of variables for each of hundreds of thousands to millions of cells in a single sample. Machine learning models are beginning to provide significant improvements in extracting information sensitively and with speed from such datasets which are often high-dimensional, sparse, and complex. Consequently, last year has seen enormous advances in deep learning applications in a variety of single-cell omics assays including genomics, transcriptomics, proteomics, metabolomics and multi-omics integration. It is highly timely to discuss the potential impact of insights generated by multi-omics machine learning platforms on the patient journey, clinical research and wider pharmaceutical sector through this miniconference.

We will cover examples and potential applications of deep learning on single-cell and other high throughput datasets in the context of:

 

  • Early diagnosis
  • Differential diagnosis against overlapping etiologies
  • Patient stratification for therapy  
  • Design of clinical trials
  • Understanding disease mechanisms
  • Drug discovery and repurposing
  • Lifestyle decisions

Target audience:

  • Drug developers advancing precision medicine and biomarker-driven science
  • Industry and academic partners running clinical trials
  • Bioinformaticians and data scientists in academia and healthcare industries interested in machine learning approaches for multi-omics data
  • Scientists interested in advancing biological understanding of disease and target identification with machine learning, single-cell and other multidimensional data

Programme:

Virtual: Zoom; all Times indicated are CET Times, Lines to open at 14:20 CET time.

TALKS:      

14:30 –14:40            Welcome and objectives; Peter Nestorov, CEO, Scailyte 

14:40 –15:00            Machine learning on Multiomics      

Christopher Yau, Professor of Artificial Intelligence at the University of Oxford and Fellow at the Alan Turing Institute, UK

15:00 –15:20            Multiomics  in industry   I   

Asif Jan, Chief Data Officer, Owkin

15:20 –15:40             Clinical applications of Multiomics                                 

Michael Brenner, Elizabeth Fay Brigham Professor of Medicine at Harvard Medical School, USA

15:40 –16:00            Multiomics  in industry   II                

Philippe Menu, Chief Medical Officer, Sophia Genetics

16:00 –16:20            Break

BRAINSTORMING SESSIONS:      

16:20 –16:50            Parallel session I (Translating Multiomics discoveries into applications for Pharma industry and Clinic)

Panel members: Industry: Dr. Philippe Menu (Sophia Genetics), Dr. Marcus Otte (Merck), Dr. Miguel Edwards (DeciBio); Academia: Prof. Michael Brenner (Harvard Medical School), Prof. Marco Ruella (University of Pennsylvania), Prof. Woongyang Park (Sungkyunkwan University, Samsung Genome Institute and Geninus); Dr Diana Stoycheva (moderator, Scailyte) 

16:20 –16:50            Parallel session II (Data Science solutions and future prospects for Multiomics and machine learning)

Panel members:  Industry:  Dr. Asif Jan (Owkin), Academia: Prof. Christopher Yau (University of Oxford); Dr. Kieran Campbell (University of Toronto), Dr. Dennis Göhlsdorf (Scailyte); Sarah Carl (moderator, Scailyte) 

16:50 –17:00            Concluding remarks, Corinne Solier, COO, Scailyte 

About Scailyte

Scailyte is an ETH Zürich spin-off with a best-in-class artificial intelligence platform for the discovery of complex disease patterns from single-cell data. Our solution provides unprecedented insight into the disease and patients’ biology and enables the discovery of new clinically-relevant biomarker signatures by uncovering human’s hidden “single-cell” secrets. 

Scailyte’s proprietary best-in-class data analysis platform ScaiVision™ associates multimodal single-cell datasets (RNA-/TCR-/BCR-seq, proteomics, etc.) with clinical endpoints, such as disease diagnosis, progression, severity, treatment response, and toxicity response to identify ultra-sensitive biomarker signatures and cell functionality states. The performance and clinically-relevant applications of Scailyte’s platform ScaiVision have been demonstrated in well established CAR-T cell therapies and various clinical projects in Oncology and Immunology.

For more information, visit www.scailyte.com and connect on social media @LinkedIn and @Twitter.

ScailyteTM and ScaiVisionTM are registered trademarks proprietary to Scailyte AG.

Recent News

Machine learning meets multi-omics for precision medicine

Bringing industry and academia together to discuss the potential impact of single-cell analytics pow

Read more

Recent News

Understanding Resistant to CAR-T Immunotherapy to Develop Better Next-generation Therapies

Register for Scailyte's webinar on "Understanding Resistant to CAR-T Immunotherapy to Develop Better

Read more

Recent News

VACANCY: Technical Lead / Product Owner for a clinical diagnostic software

Scailyte is a globally recognised spin-off from ETH Zürich and a pioneer in the field of single-cel

Read more

Recent News

VACANCY: Data Scientist in Biomarker Discovery

Scailyte is a globally recognized spin-off from ETH Zürich and a pioneer in the field of single-cel

Read more

Recent News

True precision medicine through single-cell science - Nature

ScaiVision identifies disease signatures predicting drug efficacy & drug mode of action. Precision m

Read more

Recent News

Scailyte AG Announces a partnership with Sirona DX

Scailyte AG announces a strategic partnership with Sirona DX for AI-driven end-point specific single

Read more

Recent News

WEBINAR: Supervised learning of disease-associated cell states and dynamics

Watch Scailyte's webinar on "Supervised learning of disease-associated cell states and dynamics" wit

Read more

Recent News

PODCAST: Discovering diseases with artificial intelligence

PODCAST: Discovering diseases with artificial intelligence. Listen to this episode of Binary Dreams

Read more

Recent News

01 /04

Machine learning meets multi-omics for precision medicine

Bringing industry and academia together to discuss the potential impact of single-cell analytics pow

Read more

Understanding Resistant to CAR-T Immunotherapy to Develop Better Next-generation Therapies

Register for Scailyte's webinar on "Understanding Resistant to CAR-T Immunotherapy to Develop Better

Read more

Recent News

02 /04

VACANCY: Technical Lead / Product Owner for a clinical diagnostic software

Scailyte is a globally recognised spin-off from ETH Zürich and a pioneer in the field of single-cel

Read more

VACANCY: Data Scientist in Biomarker Discovery

Scailyte is a globally recognized spin-off from ETH Zürich and a pioneer in the field of single-cel

Read more

Recent News

03 /04

True precision medicine through single-cell science - Nature

ScaiVision identifies disease signatures predicting drug efficacy & drug mode of action. Precision m

Read more

Scailyte AG Announces a partnership with Sirona DX

Scailyte AG announces a strategic partnership with Sirona DX for AI-driven end-point specific single

Read more

Recent News

04 /04

WEBINAR: Supervised learning of disease-associated cell states and dynamics

Watch Scailyte's webinar on "Supervised learning of disease-associated cell states and dynamics" wit

Read more

PODCAST: Discovering diseases with artificial intelligence

PODCAST: Discovering diseases with artificial intelligence. Listen to this episode of Binary Dreams

Read more

Recent News