Understanding Resistant to CAR-T Immunotherapy to Develop Better Next-generation Therapies

May 4 2022

CAR T therapy is changing the treatment paradigm for lymphoid malignancies. However, there are still significant challenges to be overcome as the majority of patients will eventually fail this therapy. Moreover, CAR T therapy is still not working satisfactorily in most cancer types. Dr. Ruella will provide an overview of the latest findings of his group on resistance mechanisms to CAR T immunotherapy, including the use of next-generation platforms such as single-cell RNA sequencing and functional genomics to design novel effective therapies.

The format is the following:

5 mins – introduction
20 mins – main discussion
20 min+ – Q&A

Watch the webinar here: https://youtu.be/3VYZo8VfOdk

About Scailyte

Scailyte is an ETH Zürich spin-off with a best-in-class artificial intelligence platform for the discovery of complex disease patterns from single-cell data. Our solution provides unprecedented insight into the disease and patients’ biology and enables the discovery of new clinically-relevant biomarker signatures by uncovering human’s hidden “single-cell” secrets.

Scailyte’s proprietary best-in-class data analysis platform ScaiVision™ associates multimodal single-cell datasets (RNA-/TCR-/BCR-seq, proteomics, etc.) with clinical endpoints, such as disease diagnosis, progression, severity, treatment response, and toxicity response to identify ultra-sensitive biomarker signatures and cell functionality states. The performance and clinically-relevant applications of Scailyte’s platform ScaiVision have been demonstrated in well established CAR-T cell therapies and various clinical projects in Oncology and Immunology.

For more information, visit www.scailyte.com and connect on social media @LinkedIn and @Twitter.

ScailyteTM and ScaiVisionTM are registered trademarks proprietary to Scailyte AG.

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